Research Scientist – Flow Cytometry
We are seeking a highly motivated Research Scientist to work with a small team of scientists and technologists to design, develop, validate, and optimize novel, high complexity multicolor flow cytometry-based assays for the development of high throughput clinical assays. Will include evaluating the utility of custom developed antibodies and their conjugates.
The project team will utilize flow cytometry technology to develop novel clinical assays, leveraging their deep knowledge and understanding of current multi-color flow cytometry instrumentation, antibody and fluorophore selection, and data analysis methods.
- Advanced degree in life sciences field or immunology. MS required, Ph.D. preferred.
- 5+ years experience and demonstrated understanding and proficiency with multicolor flow cytometry instrumentation
- Experience with CLIA/CAP validation and operating regulations preferred
- Responsible for all phases of assay development and implementation, including feasibility, procedure design and optimization, assay validation, SOP preparation, and implementation of new assays.
- Independently design and execute well-planned, hypothesis-driven experiments in support of assay development.
- Guide associates in planning efficient, cost-effective, and creative experiments.
- Lead multiple projects, while mentoring research associates through individual experiments and throughout the duration of projects as needed.
- Routinely perform complex data analyses and mentor research associates and peers through good data cleaning, analysis, and interpretation practices.
- Actively participate in or lead the discussion of experiment results and project status, risks, and plans forward.
- Effectively generate and present experiment findings and project progress and results in various forms, ranging from concise spreadsheets to PowerPoint presentations.
- Responsible for various administrative tasks necessary for department maintenance (inventory management, equipment maintenance, etc.).
- Develop, and guide associates through the development of Standard Operating Procedures (SOPs) in accordance with CLIA regulations and any applicable Laboratory Accreditation Standards, and other technical documents through revisions and feedback.
- Ensure adherence to all laboratory SOPs and troubleshoot issues in both experiments and routinely performed procedures.
- Ensure project documentation, including electronic laboratory notebooks, are sufficiently maintained to evaluate, trouble-shoot and reproduce experimental results
- Provide training and support to laboratory staff as needed, primarily during the implementation of new procedures or modifications based on assay optimization projects.
- Serve as a technical resource to fellow department team members, especially research associates, as they navigate individual projects and experiments.
- Collaborate with various levels of laboratory staff for completion of special projects as assigned.
- Other duties as assigned
- This role will have some flexibility in scheduling, weekly schedules may vary depending on project developments and needs
- While occasional telework is a possibility, this role must regularly report to work on-site in our Irvine office
- Physical demands: role holders will regularly sit and/or stand for long periods of time. Role holders will split their time between an office environment and the laboratory, where they will regularly come into contact with chemical reagents and biological substances. We provide all necessary PPE and safety training to ensure role holders are aware of hazards and prepared to operate lab equipment safely.
Pathnostics is proud to be an equal opportunity employer.